Age-Related Osteogenic Potential of Mesenchymal Stromal Stem Cells from Human Vertebral Bone Marrow

D’Ippolito, Gianluca; C. Schiller, Paul; Ricordi, Camillo; A. Roos, Bernard; A. Howard, Guy

doi:10.1359/jbmr.1999.14.7.1115

Public

Age-Related Osteogenic Potential of Mesenchymal Stromal Stem Cells from Human Vertebral Bone Marrow

Published in Journal of Bone and Mineral Research • Jul 1, 1999

Authors:

Gianluca D’Ippolito

Paul C. Schiller

Camillo Ricordi

Abstract

Mesenchymal stem cells (MSCs) residing in bone marrow (BM) are the progenitors for osteoblasts and for several other cell types. In humans, the age-related decrease in bone mass could reflect decreased osteoblasts secondary to an age-related loss of osteoprogenitors. To test this hypothesis, BM cell...

Subject

Mesenchymal stem cell

Stromal cell

Human bone

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