Age-related osteogenic potential of mesenchymal stromal stem cells from human vertebral bone marrow.

G, D'Ippolito; PC, Schiller; C, Ricordi; BA, Roos; GA, Howard

doi:10.1359/jbmr.1999.14.7.1115

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Age-related osteogenic potential of mesenchymal stromal stem cells from human vertebral bone marrow.

Shared by NobleBlocks on Jul 1, 1999 • 12:00 AM UTC

Authors:

D'Ippolito G

Schiller PC

Ricordi C

Abstract

Mesenchymal stem cells (MSCs) residing in bone marrow (BM) are the progenitors for osteoblasts and for several other cell types. In humans, the age-related decrease in bone mass could reflect decreased osteoblasts secondary to an age-related loss of osteoprogenitors. To test this hypothesis, BM cell...

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