Renoprotective Effect of the Angiotensin-Receptor Antagonist Irbesartan in Patients with Nephropathy Due to Type 2 Diabetes

J. Lewis, Edmund; G. Hunsicker, Lawrence; R. Clarke, William; Berl, Tomás; A. Pohl, Marc; B. Lewis, Julia; Ritz, Eberhard; C. Atkins, Robert; Rohde, Richard; Raz, Itamar

doi:10.1056/nejmoa011303

Public

Renoprotective Effect of the Angiotensin-Receptor Antagonist Irbesartan in Patients with Nephropathy Due to Type 2 Diabetes

Published in New England Journal of Medicine • Sep 20, 2001

Authors:

Edmund J. Lewis

Lawrence G. Hunsicker

William R. Clarke

Abstract

BACKGROUND: It is unknown whether either the angiotensin-II-receptor blocker irbesartan or the calcium-channel blocker amlodipine slows the progression of nephropathy in patients with type 2 diabetes independently of its capacity to lower the systemic blood pressure. METHODS: We randomly assigned 17...

Subject

Irbesartan

Amlodipine

Medicine

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