Synchronized renal tubular cell death involves ferroptosis

Linkermann, Andreas; Skouta, Rachid; Himmerkus, Nina; R. Mulay, Shrikant; Dewitz, Christin; De Zen, Federica; Prókai, Ágnes; Zuchtriegel, Gabriele; Krombach, Fritz; Welz, Patrick-Simon; Weinlich, Ricardo; Vanden Berghe, Tom; Vandenabeele, Peter; Pasparakis, Manolis; Bleich, Markus; M. Weinberg, Joel; A. Reichel, Christoph; Hinrich Bräsen, Jan; Kunzendorf, Ulrich; Anders, Hans‐Joachim; R. Stockwell, Brent; R. Green, Douglas; Krautwald, Stefan

doi:10.1073/pnas.1415518111

Public

Synchronized renal tubular cell death involves ferroptosis

Published in Proceedings of the National Academy of Sciences • Nov 10, 2014

Authors:

Andreas Linkermann

Rachid Skouta

Nina Himmerkus

Abstract

Receptor-interacting protein kinase 3 (RIPK3)-mediated necroptosis is thought to be the pathophysiologically predominant pathway that leads to regulated necrosis of parenchymal cells in ischemia-reperfusion injury (IRI), and loss of either Fas-associated protein with death domain (FADD) or caspase-8...

Subject

Necrosis

Programmed cell death

Ischemia

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!