Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomas.

V, Gismondi; M, Meta; L, Bonelli; P, Radice; P, Sala; L, Bertario; A, Viel; M, Fornasarig; A, Arrigoni; M, Gentile; de Leon M, Ponz; L, Anselmi; C, Mareni; P, Bruzzi; L, Varesco

doi:10.1002/ijc.20054

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Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomas.

Shared by NobleBlocks on May 1, 2004 • 12:00 AM UTC

Authors:

Gismondi V

Meta M

Bonelli L

Abstract

Biallelic germline mutations in the base excision repair gene MYH have been reported in patients with multiple colorectal adenomas and cancer and in sporadic FAP patients not showing a detectable APC germline mutation. In this study, the prevalence of the common Y165C and G382D germline variants of ...

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