Optogenetic Stimulation of MCH Neurons Increases Sleep

Rani Konadhode, Roda; Pelluru, Dheeraj; Blanco‐Centurion, Carlos; Zayachkivsky, Andrew; Liu, Mei; W. Uhde, Thomas; Bailey Glen, W.; N. van den Pol, Anthony; J. Mulholland, Patrick; J. Shiromani, Priyattam

doi:10.1523/jneurosci.1225-13.2013

Public

Optogenetic Stimulation of MCH Neurons Increases Sleep

Published in Journal of Neuroscience • Jun 19, 2013

Authors:

Roda Rani Konadhode

Dheeraj Pelluru

Carlos Blanco‐Centurion

Abstract

Melanin concentrating hormone (MCH) is a cyclic neuropeptide present in the hypothalamus of all vertebrates. MCH is implicated in a number of behaviors but direct evidence is lacking. To selectively stimulate the MCH neurons the gene for the light-sensitive cation channel, channelrhodopsin-2, was in...

Subject

Optogenetics

Stimulation

Melanin-concentrating hormone

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