A Comparison of Enalapril with Hydralazine–Isosorbide Dinitrate in the Treatment of Chronic Congestive Heart Failure

N. Cohn, Jay; R. Johnson, Gary; Ziesche, Susan; R. Cobb, Frederick; S. Francis, Gary; E. Tristani, Felix; F. Smith, Raphael; Bruce Dunkman, W.; S. Loeb, Henry; Wong, Maylene; Bhat, Geetha; Goldman, Steven; D. Fletcher, Ross; E. Doherty, James; V. Hughes, C.; E. Carson, Peter; Cintrón, Guillermo; Shabetai, Ralph; Haakenson, Clair

doi:10.1056/nejm199108013250502

Public

A Comparison of Enalapril with Hydralazine–Isosorbide Dinitrate in the Treatment of Chronic Congestive Heart Failure

Published in New England Journal of Medicine • Aug 1, 1991

Authors:

Jay N. Cohn

Gary R. Johnson

Susan Ziesche

Abstract

BACKGROUND: To define better the efficacy of vasodilator therapy in the treatment of chronic congestive heart failure, we compared the effects of hydralazine and isosorbide dinitrate with those of enalapril in 804 men receiving digoxin and diuretic therapy for heart failure. The patients were random...

Subject

Isosorbide dinitrate

Medicine

Hydralazine

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