Human Solid Tumors Contain High Endothelial Venules: Association with T- and B-Lymphocyte Infiltration and Favorable Prognosis in Breast Cancer

Martinet, Ludovic; Garrido, Ignacio; Filleron, Thomas; Le Guellec, Sophie; Bellard, Elisabeth; Fournié, Jean‐Jacques; Rochaix, Philippe; Girard, Jean‐Philippe

doi:10.1158/0008-5472.can-11-0431

Public

Human Solid Tumors Contain High Endothelial Venules: Association with T- and B-Lymphocyte Infiltration and Favorable Prognosis in Breast Cancer

Published in Cancer Research • Aug 16, 2011

Authors:

Ludovic Martinet

Ignacio Garrido

Thomas Filleron

Abstract

The mechanisms governing infiltration of lymphocytes into tumors remain poorly characterized, in spite of the critical impact of these cells on patient prognosis and therapeutic responses. High endothelial venules (HEV) are blood vessels found in lymphoid tissues, specialized in lymphocyte recruitme...

Subject

Infiltration (HVAC)

Tumor-infiltrating lymphocytes

CD8

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