Boceprevir for Previously Treated Chronic HCV Genotype 1 Infection

R. Bacon, Bruce; C. Gordon, Stuart; Lawitz, Eric; Marcellin, Patrick; M. Vierling, John; Zeuzem, Stefan; Poordad, Fred; Goodman, Zachary; L. Sings, Heather; Boparai, Navdeep; Burroughs, Margaret; A. Brass, Clifford; K. Albrecht, Janice; Esteban, Rafael

doi:10.1056/nejmoa1009482

Public

Boceprevir for Previously Treated Chronic HCV Genotype 1 Infection

Published in New England Journal of Medicine • Mar 30, 2011

Authors:

Bruce R. Bacon

Stuart C. Gordon

Eric Lawitz

Abstract

BACKGROUND: In patients with chronic infection with hepatitis C virus (HCV) genotype 1 who do not have a sustained response to therapy with peginterferon-ribavirin, outcomes after retreatment are suboptimal. Boceprevir, a protease inhibitor that binds to the HCV nonstructural 3 (NS3) active site, ha...

Subject

Boceprevir

Medicine

Ribavirin

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