Nucleophosmin is recognized by a cytotoxic T cell line derived from a rectal carcinoma patient

Swoboda, Rolf; Somasundaram, Rajasekharan; Caputo, Laura; Berencsi, Klára; von Franzke, Paul; D. Taylor, Douglas; M. Marincola, Francesco; J. Meropol, Neal; R. Sigurdson, Elin; P. Miller, Eric; Herlyn, Dorothee

doi:10.1002/ijc.25133

Public

Nucleophosmin is recognized by a cytotoxic T cell line derived from a rectal carcinoma patient

Published in International Journal of Cancer • Dec 21, 2009

Authors:

Rolf Swoboda

Rajasekharan Somasundaram

Laura Caputo

Abstract

Immunotherapy of colorectal carcinoma (CRC) has great promise as the presence of T lymphocytes in CRC tissues in situ is correlated with reduced recurrence and increased survival. Thus, identification of the antigens recognized by T cells of CRC patients may permit development of vaccines with poten...

Subject

Cytotoxic T cell

CTL*

Antigen

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