Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Gao, Guangping; R. Alvira, Mauricio; Wang, Lili; Calcedo, Roberto; Johnston, Julie; M. Wilson, James

doi:10.1073/pnas.182412299

Public

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Published in Proceedings of the National Academy of Sciences • Aug 21, 2002

Authors:

Guangping Gao

Mauricio R. Alvira

Lili Wang

Abstract

Tissues from rhesus monkeys were screened by PCR for the presence of sequences homologous to known adeno-associated virus (AAV) serotypes 1-6. DNA spanning entire rep-cap ORFs from two novel AAVs, called AAV7 and AAV8, were isolated. Sequence comparisons among these and previously described AAVs rev...

Subject

Adeno-associated virus

Biology

Virology

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!