Phase II, Randomized Study of Concomitant Chemoradiotherapy Followed by Surgery and Adjuvant Capecitabine Plus Oxaliplatin (CAPOX) Compared With Induction CAPOX Followed by Concomitant Chemoradiotherapy and Surgery in Magnetic Resonance Imaging–Defined, Locally Advanced Rectal Cancer: Grupo Cáncer de Recto 3 Study

Fernández-Martos, Carlos; Pericay, Carles; Aparicio, Jorge; Salud, Antonieta; J. Safont, M.; Massutí, Bartomeu; Vera, Ruth; Escudero, P.; Maurel, Joan; Marcuello, Eugenio; Mengual, J.; Saigí, E.; Estevan, Rafael; Mira, Moises; Polo, Sonia; Lluch Hernández, Ana; Gallén, Manuel; Arias, Fernando; Serra, Javier; Alonso, Vicente

doi:10.1200/jco.2009.25.8541

Public

Phase II, Randomized Study of Concomitant Chemoradiotherapy Followed by Surgery and Adjuvant Capecitabine Plus Oxaliplatin (CAPOX) Compared With Induction CAPOX Followed by Concomitant Chemoradiotherapy and Surgery in Magnetic Resonance Imaging–Defined, Locally Advanced Rectal Cancer: Grupo Cáncer de Recto 3 Study

Published in Journal of Clinical Oncology • Jan 12, 2010

Authors:

Carlos Fernández-Martos

Carles Pericay

Jorge Aparicio

Abstract

PURPOSE The optimal therapeutic sequence of the adjuvant chemotherapy component of preoperative chemoradiotherapy (CRT) for patients with locally advanced rectal cancer is controversial. Induction chemotherapy before preoperative CRT may be associated with better efficacy and compliance. PATIENTS AN...

Subject

Capecitabine

Medicine

Oxaliplatin

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