Calcitonin Gene–Related Peptide Receptor Antagonist BIBN 4096 BS for the Acute Treatment of Migraine

Olesen, Jes; Diener, Hans‐Christoph; W. Husstedt, Ingo; J. Goadsby, Peter; B. Hall, David; Meier, Ulrich; Pollentier, Stephane; M. Lesko, Lynna

doi:10.1056/nejmoa030505

Public

Calcitonin Gene–Related Peptide Receptor Antagonist BIBN 4096 BS for the Acute Treatment of Migraine

Published in New England Journal of Medicine • Mar 10, 2004

Authors:

Jes Olesen

Hans‐Christoph Diener

Ingo W. Husstedt

Abstract

BACKGROUND: Calcitonin gene-related peptide (CGRP) may have a causative role in migraine. We therefore hypothesized that a CGRP-receptor antagonist might be effective in the treatment of migraine attacks. METHODS: In an international, multicenter, double-blind, randomized clinical trial of BIBN 4096...

Subject

Calcitonin gene-related peptide

Migraine

Antagonist

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