Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils.

E Lorant, D; D. Patel, Kamala; M McIntyre, T; P McEver, R; M Prescott, S; A. Zimmerman, Guy

doi:10.1083/jcb.115.1.223

Public

Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils.

Published in The Journal of Cell Biology • Oct 1, 1991

Authors:

D E Lorant

Kamala D. Patel

T M McIntyre

Abstract

The adhesion of polymorphonuclear leukocytes (PMNs) to vascular endothelial cells (EC) is an early and fundamental event in acute inflammation. This process requires the regulated expression of molecules on both the EC and PMN. EC stimulated with histamine or thrombin coexpress two proadhesive molec...

Subject

Juxtacrine signalling

Cell biology

Cell adhesion molecule

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