Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein–α

The stromal microenvironment of tumors, which is a mixture of hematopoietic and mesenchymal cells, suppresses immune control of tumor growth. A stromal cell type that was first identified in human cancers expresses fibroblast activation protein-α (FAP). We created a transgenic mouse in which FAP-exp... View More