A Single-Dose Placebo-Controlled Study of AMG 162, a Fully Human Monoclonal Antibody to RANKL, in Postmenopausal Women

Bekker, Pirow; Holloway, Donna; S Rasmussen, Amy; Murphy, Robyn; W. Martin, Steven; T. Leese, Philip; B. Holmes, Gregory; R. Dunstan, Colin; M. DePaoli, Alex

doi:10.1359/jbmr.040305

Public

A Single-Dose Placebo-Controlled Study of AMG 162, a Fully Human Monoclonal Antibody to RANKL, in Postmenopausal Women

Published in Journal of Bone and Mineral Research • Jul 1, 2004

Authors:

Pirow Bekker

Donna Holloway

Amy S Rasmussen

Abstract

UNLABELLED: The safety and bone antiresorptive effect of a single subcutaneous dose of AMG 162, a human monoclonal antibody to RANKL, was investigated in 49 postmenopausal women. AMG 162 is a potent antiresorptive agent for diseases such as osteoporosis. INTRODUCTION: RANKL is an essential osteoclas...

Subject

Medicine

Placebo

Bone remodeling

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!