Multicentre phase II trial of trastuzumab and capecitabine in patients with HER2 overexpressing metastatic pancreatic cancer

Harder, Jan; Ihorst, Gabriele; Heinemann, Volker; Hofheinz, Ralf‐Dieter; Moehler, Markus; Buechler, Peter; Kloeppel, Günter; Röcken, Christoph; Bitzer, Michael; Boeck, Stefan; Endlicher, Esther; Reinacher-Schick, A.; Schmoor, Claudia; Geißler, Michael

doi:10.1038/bjc.2012.18

Public

Multicentre phase II trial of trastuzumab and capecitabine in patients with HER2 overexpressing metastatic pancreatic cancer

Published in British Journal of Cancer • Feb 28, 2012

Authors:

Jan Harder

Gabriele Ihorst

Volker Heinemann

Abstract

BACKGROUND: New therapeutic options for metastatic pancreatic cancer are urgently needed. In pancreatic cancer, overexpression of the epidermal growth factor receptor 2 (HER2) has been reported in up to 45%. This multicentre phase II study investigated the efficacy and toxicity of the HER2 antibody ...

Subject

Capecitabine

Medicine

Trastuzumab

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