Hyperfunction of the Hypothalamic-Pituitary Axis in Women with Polycystic Ovarian Disease: Indirect Evidence for Partial Gonadotroph Desensitization*

Waldstreicher, Joanne; Santoro, Nanette; E. Hall, Janet; Filicori, Marco; F. Crowley, William

doi:10.1210/jcem-66-1-165

Public

Hyperfunction of the Hypothalamic-Pituitary Axis in Women with Polycystic Ovarian Disease: Indirect Evidence for Partial Gonadotroph Desensitization*

Published in The Journal of Clinical Endocrinology & Metabolism • Jan 1, 1988

Authors:

Joanne Waldstreicher

Nanette Santoro

Janet E. Hall

Abstract

To examine gonadotropin secretory frequency as a component of the disordered neuroendocrine regulation of gonadotropin secretion in women with polycystic ovarian disease (PCOD), we measured serum gonadotropin concentrations in 12 women with PCOD at 10-min intervals for periods of 12-24 h. The patter...

Subject

Desensitization (medicine)

Medicine

Endocrinology

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