Type 2 alveolar cells are stem cells in adult lung

E. Barkauskas, Christina; J. Cronce, Michael; R. Rackley, Craig; Bowie, Emily; R. Keene, Douglas; R. Stripp, Barry; H. Randell, Scott; W. Noble, Paul; L.M. Hogan, Brigid

doi:10.1172/jci68782

Public

Type 2 alveolar cells are stem cells in adult lung

Published in Journal of Clinical Investigation • Jun 9, 2013

Authors:

Christina E. Barkauskas

Michael J. Cronce

Craig R. Rackley

Abstract

Gas exchange in the lung occurs within alveoli, air-filled sacs composed of type 2 and type 1 epithelial cells (AEC2s and AEC1s), capillaries, and various resident mesenchymal cells. Here, we use a combination of in vivo clonal lineage analysis, different injury/repair systems, and in vitro culture ...

Subject

Biology

Mesenchymal stem cell

Stem cell

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!