Therapeutic action of tranexamic acid in hereditary haemorrhagic telangiectasia (HHT): Regulation of ALK-1/endoglin pathway in endothelial cells

Fernández-L, Africa; M. Garrido‐Martín, Eva; Sanz-Rodrı́guez, Francisco; Ramirez, Jose-Ramon; Morales‐Angulo, Carmelo; Zarrabeitia, Roberto; Perez-Molino, Alfonso; Bernabéu, Carmelo; M. Botella, Luisa

doi:10.1160/th06-07-0373

Public

Therapeutic action of tranexamic acid in hereditary haemorrhagic telangiectasia (HHT): Regulation of ALK-1/endoglin pathway in endothelial cells

Published in Thrombosis and Haemostasis • Jan 1, 2007

Authors:

Africa Fernández-L

Eva M. Garrido‐Martín

Francisco Sanz-Rodrı́guez

Abstract

Recurrent epistaxis is the most frequent clinical manifestation of hereditary haemorrhagic telangiectasia (HHT). Its treatment is difficult. Our objective was to assess the use of tranexamic acid (TA), an antifibrinolytic drug, for the treatment of epistaxis in HHT patients and to investigate in vit...

Subject

Endoglin

Medicine

Tranexamic acid

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