Molecular Imaging of Microglial Activation in Amyotrophic Lateral Sclerosis

Corcia, Philippe; Tauber, Clovis; Vercoullie, Johnnie; Arlicot, Nicolas; Prunier, Caroline; Praline, Julien; Guillaume, Nicolas; Venel, Y.; Hommet, Caroline; Baulieu, Jean‐Louis; Cottier, Jean‐Philippe; Roussel, Catherine; Kassiou, Michael; Guilloteau, Denis; Santiago Ribeiro, Maria-Joao

doi:10.1371/journal.pone.0052941

Public

Molecular Imaging of Microglial Activation in Amyotrophic Lateral Sclerosis

Published in PLoS ONE • Dec 31, 2012

Authors:

Philippe Corcia

Clovis Tauber

Johnnie Vercoullie

Abstract

There is growing evidence of activated microglia and inflammatory processes in the cerebral cortex in amyotrophic lateral sclerosis (ALS). Activated microglia is characterized by increased expression of the 18 kDa translocator protein (TSPO) in the brain and may be a useful biomarker of inflammation...

Subject

Amyotrophic lateral sclerosis

Microglia

Neuroscience

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