Multicenter Evaluation of a Sequence-Based Protocol for Subtyping Shiga Toxins and Standardizing Stx Nomenclature

Scheutz, Flemming; D. Teel, Louise; Beutin, Lothar; Piérard, Denis; Buvens, Glenn; Karch, Helge; Mellmann, Alexander; Caprioli, Alfredo; Tozzoli, Rosangela; Morabito, Stefano; Strockbine, Nancy; R. Melton‐Celsa, Angela; Álvarez Sánchez, María; Persson, Søren; D. O’Brien, Alison

doi:10.1128/jcm.00860-12

Public

Multicenter Evaluation of a Sequence-Based Protocol for Subtyping Shiga Toxins and Standardizing Stx Nomenclature

Published in Journal of Clinical Microbiology • Jul 4, 2012

Authors:

Flemming Scheutz

Louise D. Teel

Lothar Beutin

Abstract

When Shiga toxin-producing Escherichia coli (STEC) strains emerged as agents of human disease, two types of toxin were identified: Shiga toxin type 1 (Stx1) (almost identical to Shiga toxin produced by Shigella dysenteriae type 1) and the immunologically distinct type 2 (Stx2). Subsequently, numerou...

Subject

Shiga toxin

Subtyping

Shigella dysenteriae

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