Evaluation of a Minimally Invasive Cell Sampling Device Coupled with Assessment of Trefoil Factor 3 Expression for Diagnosing Barrett's Esophagus: A Multi-Center Case–Control Study

S. Ross-Innes, Caryn; Debiram–Beecham, Irene; O’Donovan, Maria; Walker, Elaine; Varghese, Sybil; Lao-Sirieix, Pierre; Lovat, Laurence; M Griffin, S; Ragunath, Krish; Haidry, Rehan; S. Sami, Sarmed; Kaye, Philip; Novelli, Marco; Disep, Babett; Ostler, Richard; Aigret, Benoit; V. North, Bernard; Bhandari, Pradeep; Haycock, Adam; Morris, Danielle; Attwood, Stephen; Dhar, Anjan; Rees, Colin; D. Rutter, Matthew; Sasieni, Peter; C. Fitzgerald, Rebecca; behalf of the BEST2 Study Group, on

doi:10.1371/journal.pmed.1001780

Public

Evaluation of a Minimally Invasive Cell Sampling Device Coupled with Assessment of Trefoil Factor 3 Expression for Diagnosing Barrett's Esophagus: A Multi-Center Case–Control Study

Published in PLoS Medicine • Jan 29, 2015

Authors:

Caryn S. Ross-Innes

Irene Debiram–Beecham

Maria O’Donovan

Abstract

BACKGROUND: Barrett's esophagus (BE) is a commonly undiagnosed condition that predisposes to esophageal adenocarcinoma. Routine endoscopic screening for BE is not recommended because of the burden this would impose on the health care system. The objective of this study was to determine whether a nov...

Subject

Medicine

Barrett's esophagus

Endoscopy

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