Functional Mesenchymal Stem Cells Derived From Human Induced Pluripotent Stem Cells Attenuate Limb Ischemia in Mice

Lian, Qizhou; Zhang, Yuelin; Zhang, Jinqiu; Kun Zhang, Hua; Wu, Xingang; Zhang, Yang; Fu-Yuen Lam, Francis; Kang, Sarang; Xia, Jian‐Chuan; Lai, Wenchu; Au, Ka‐Wing; Y. Chow, Y.; Siu, Chung‐Wah; Neng Lee, Chuen; Tse, Hung‐Fat

doi:10.1161/circulationaha.109.898312

Public

Functional Mesenchymal Stem Cells Derived From Human Induced Pluripotent Stem Cells Attenuate Limb Ischemia in Mice

Published in Circulation • Feb 23, 2010

Authors:

Qizhou Lian

Yuelin Zhang

Jinqiu Zhang

Abstract

BACKGROUND: Aging and aging-related disorders impair the survival and differentiation potential of bone marrow mesenchymal stem cells (MSCs) and limit their therapeutic efficacy. Induced pluripotent stem cells (iPSCs) may provide an alternative source of functional MSCs for tissue repair. This study...

Subject

Mesenchymal stem cell

Induced pluripotent stem cell

Medicine

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