Adipophilin/perilipin‐2 as a lipid droplet‐specific marker for metabolically active cells and diseases associated with metabolic dysregulation

K. Straub, Beate; Gyoengyoesi, Benedek; Koenig, Maria; Hashani, M; Pawella, L; Herpel, Esther; Mueller, Wolf; Macher‐Goeppinger, Stephan; Heid, Hans; Schirmacher, Peter

doi:10.1111/his.12038

Public

Adipophilin/perilipin‐2 as a lipid droplet‐specific marker for metabolically active cells and diseases associated with metabolic dysregulation

Published in Histopathology • Oct 3, 2012

Authors:

Beate K. Straub

Benedek Gyoengyoesi

Maria Koenig

Abstract

AIMS: Lipid droplets (LDs) are dynamic storage compartments for energy-rich fats that are nearly ubiquitously present in eukaryotic cells, exerting tissue-specific functions in metabolically active cell types, and are increased in conditions following cellular damage or lipid overload. The LD-cytopl...

Subject

Perilipin

Lipid droplet

Steatosis

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