A Comparative Efficacy Trial in Germany in Infants Who Received Either the Lederle/Takeda Acellular Pertussis Component DTP (DTaP) Vaccine, the Lederle Whole-Cell Component DTP Vaccine, or DT Vaccine

Stehr, K; D. Cherry, James; Heininger, Ulrich; Schmitt‐Grohé, Sabina; A. Überall, Michael; Laussucq, Suzanne; Eckhardt, Thomas; Meyer, Martin; Engelhardt, Rita; D. Christenson, Peter; Pertussis Vaccine Study Group, the

doi:10.1542/peds.101.1.1

Public

A Comparative Efficacy Trial in Germany in Infants Who Received Either the Lederle/Takeda Acellular Pertussis Component DTP (DTaP) Vaccine, the Lederle Whole-Cell Component DTP Vaccine, or DT Vaccine

Published in PEDIATRICS • Jan 1, 1998

Authors:

K Stehr

James D. Cherry

Ulrich Heininger

Abstract

BACKGROUND: The goal of the trial was to determine the efficacy of a multicomponent acellular pertussis vaccine against Bordetella illnesses in comparison with a whole-cell product and DT. DESIGN: In a randomized, double-blind fashion, 2- to 4-month-old infants received 4 doses of either DTP or DTaP...

Subject

Medicine

Reactogenicity

Pediatrics

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