Quantitative CARS Molecular Fingerprinting of Single Living Cells with the Use of the Maximum Entropy Method

Fast CARS: The cell-death process was observed in real time at the subcellular level by coherent anti-Stokes Raman microspectroscopy, an extension of anti-Stokes Raman scattering (CARS) microscopy. Changes in the chemical contrast during the dying process can be clearly resolved (see picture).