Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques

Tacke, Frank; Álvarez, David; Kaplan, Theodore; Jakubzick, Claudia; Spanbroek, Rainer; Llodrá, Jaime; Garin, Alexandre; Liu, Jianhua; Mack, Matthias; van Rooijen, Nico; A. Lira, Sérgio; J. R. Habenicht, Andreas; J. Randolph, Gwendalyn

doi:10.1172/jci28549

Public

Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques

Published in Journal of Clinical Investigation • Jan 2, 2007

Authors:

Frank Tacke

David Álvarez

Theodore Kaplan

Abstract

Monocytes participate critically in atherosclerosis. There are 2 major subsets expressing different chemokine receptor patterns: CCR2(+)CX3CR1(+)Ly-6C(hi) and CCR2(-)CX3CR1(++)Ly-6C(lo) monocytes. Both C-C motif chemokine receptor 2 (CCR2) and C-X(3)-C motif chemokine receptor 1 (CX3CR1) are linked ...

Subject

CCR2

CX3CR1

Monocyte

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!