Bystander-Activated Memory CD8 T Cells Control Early Pathogen Load in an Innate-like, NKG2D-Dependent Manner

Chu, Talyn; J. Tyznik, Aaron; Roepke, Sarah; M. Berkley, Amy; S. Woodward Davis, Amanda; Pattacini, Laura; J Bevan, M; Zehn, Dietmar; Prlic, Martin

doi:10.1016/j.celrep.2013.02.020

Public

Bystander-Activated Memory CD8 T Cells Control Early Pathogen Load in an Innate-like, NKG2D-Dependent Manner

Published in Cell Reports • Mar 1, 2013

Authors:

Talyn Chu

Aaron J. Tyznik

Sarah Roepke

Abstract

During an infection the antigen-nonspecific memory CD8 T cell compartment is not simply an inert pool of cells, but becomes activated and cytotoxic. It is unknown how these cells contribute to the clearance of an infection. We measured the strength of T cell receptor (TCR) signals that bystander-act...

Subject

Bystander effect

NKG2D

Innate immune system

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!