Neopeltolide, a macrolide from a lithistid sponge of the family Neopeltidae.

E Wright, Amy; Cook Botelho, Julianne; Guzmán, Esther; Harmody, Dedra; Linley, Patricia; J McCarthy, Peter; P Pitts, Tara; A Pomponi, Shirley; K Reed, John

doi:10.1021/np060597h

Public

Neopeltolide, a macrolide from a lithistid sponge of the family Neopeltidae.

Published in Journal of natural products • Mar 1, 2007

NobleIDark:/48914/w1/20260526/69CC923FRecord on NobleID

Authors:

Amy E Wright

,

Julianne Cook Botelho

,

Esther Guzmán

Abstract

A new marine-derived macrolide designated as neopeltolide (1) has been isolated from a deep-water sponge of the family Neopeltidae. Its structure was elucidated on the basis of spectroscopic data interpretation. Neopeltolide (1) is a potent inhibitor of the in vitro proliferation of the A-549 human ...

Discussions