Curcumin-Loaded Nanoparticles Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer’s Disease Model <i>via</i> Canonical Wnt/β-Catenin Pathway

Kant Tiwari, Shashi; Agarwal, Swati; Seth, Brashket; Yadav, Anuradha; Nair, Saumya; K. Bhatnagar, P.; Karmakar, Madhumita; Kumari, Manisha; Kumar Singh Chauhan, Lalit; Kumar Patel, Devendra; Srivastava, Vikas; Singh, Dhirendra; K. Gupta, Shailendra; Tripathi, Anurag; Kumar Chaturvedi, Rajnish; C. Gupta, Kailash

doi:10.1021/nn405077y

Public

Curcumin-Loaded Nanoparticles Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer’s Disease Model via Canonical Wnt/β-Catenin Pathway

Published in ACS Nano • Dec 4, 2013

Authors:

Shashi Kant Tiwari

Swati Agarwal

Brashket Seth

Abstract

Neurogenesis, a process of generation of new neurons, is reported to be reduced in several neurodegenerative disorders including Alzheimer's disease (AD). Induction of neurogenesis by targeting endogenous neural stem cells (NSC) could be a promising therapeutic approach to such diseases by influenci...

Subject

Neurogenesis

Curcumin

Neural stem cell

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