A yeast estrogen screen for examining the relative exposure of cells to natural and xenoestrogens.

F Arnold, S; K Robinson, M; C Notides, A; J Guillette, L; A McLachlan, J

doi:10.1289/ehp.96104544

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A yeast estrogen screen for examining the relative exposure of cells to natural and xenoestrogens.

Shared by NobleBlocks on May 1, 1996 • 12:00 AM UTC

Authors:

S F Arnold

M K Robinson

A C Notides

Abstract

Xenoestrogens, such as o,p'-DDT and octyl phenol (OP), have been associated with reproductive abnormalities in various wildlife species. Xenoestrogens mimic the natural estrogen 17 beta-estradiol and compete for binding to the estrogen receptor. Even though the affinity of o,p'-DDT and OP for the es...

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