High Phosphorus Diet Rapidly Induces Nephrocalcinosis and Proximal Tubular Injury in Rats.

The development of nephrocalcinosis and the time course of changes in kidney function, especially proximal tubular function, were studied in young male rats fed a high-phosphorus diet. The animals were fed a purified diet with a phosphorus content of either 0.5% (normal phosphorus diet) or 1.5% (hig... View More