Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project

R. Carson, Kenneth; M. Evens, Andrew; Richey, Elizabeth; M. Habermann, Thomas; Focosi, Daniele; F. Seymour, John; P. Laubach, Jacob; D. Bawn, Susie; I. Gordon, Leo; N. Winter, Jane; R. Furman, Richard; M. Vose, Julie; D. Zelenetz, Andrew; Mamtani, Ronac; W. Raisch, Dennis; W. Dorshimer, Gary; T. Rosen, Steven; Muro, Kenji; R. Gottardi-Littell, Numa; L. Talley, Robert; Sartor, Oliver; Green, David; O. Major, Eugene; L. Bennett, Charles

doi:10.1182/blood-2008-10-186999

Public

Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project

Published in Blood • Mar 6, 2009

Authors:

Kenneth R. Carson

Andrew M. Evens

Elizabeth Richey

Abstract

Rituximab improves outcomes for persons with lymphoproliferative disorders and is increasingly used to treat immune-mediated illnesses. Recent reports describe 2 patients with systemic lupus erythematosus and 1 with rheumatoid arthritis who developed progressive multifocal leukoencephalopathy (PML) ...

Subject

Rituximab

Medicine

Progressive multifocal leukoencephalopathy

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