Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCF TIR1 in Mediating Auxin Response

Schwechheimer, Claus; Serino, Giovanna; Callis, Judy; L. Crosby, William; Lyapina, Svetlana; J. Deshaies, Raymond; M. Gray, William; Estelle, Mark; Deng, Xing‐Wang

doi:10.1126/science.1059776

Public

Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCF TIR1 in Mediating Auxin Response

Published in Science • May 18, 2001

Authors:

Claus Schwechheimer

Giovanna Serino

Judy Callis

Abstract

The COP9 signalosome is an evolutionary conserved multiprotein complex of unknown function that acts as a negative regulator of photomorphogenic seedling development in Arabidopsis. Here, we show that plants with reduced COP9 signalosome levels had decreased auxin response similar to loss-of-functio...

Subject

COP9 signalosome

Ubiquitin ligase

Ubiquitin

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