Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device

Talasaz, AmirAli; A. Powell, Ashley; Huber, David; G. Berbee, James; Roh, Kyung‐Ho; Yu, Wong; Xiao, Wenzhong; M. Davis, Mark; F. W. Pease, R.; Mindrinos, Michael; S. Jeffrey, Stefanie; W. Davis, Ronald

doi:10.1073/pnas.0813188106

Public

Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device

Published in Proceedings of the National Academy of Sciences • Feb 21, 2009

Authors:

AmirAli Talasaz

Ashley A. Powell

David Huber

Abstract

The enumeration of rare circulating epithelial cells (CEpCs) in the peripheral blood of metastatic cancer patients has shown promise for improved cancer prognosis. Moving beyond enumeration, molecular analysis of CEpCs may provide candidate surrogate endpoints to diagnose, treat, and monitor maligna...

Subject

Circulating tumor cell

Enumeration

Cancer cell

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