Myostatin, a transforming growth factor-? superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct

Sharma, Mridula; Kambadur, Ravi; G. Matthews, Kenneth; Gregory Somers, W.; Devlin, Gerard; V. Conaglen, John; J. Fowke, P.; J. Bass, John

doi:10.1002/(sici)1097-4652(199907)180:1<1::aid-jcp1>3.0.co;2-v

Public

Myostatin, a transforming growth factor-? superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct

Published in Journal of Cellular Physiology • Jul 1, 1999

Authors:

Mridula Sharma

Ravi Kambadur

Kenneth G. Matthews

Abstract

Myostatin is a secreted growth and differentiating factor (GDF-8) that belongs to the transforming growth factor-beta (TGF-beta) superfamily. Targeted disruption of the myostatin gene in mice and a mutation in the third exon of the myostatin gene in double-muscled Belgian Blue cattle breed result in...

Subject

Myostatin

Biology

Internal medicine

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!