Intramyocardial Injection of Autologous Bone Marrow-Derived Ex Vivo Expanded Mesenchymal Stem Cells in Acute Myocardial Infarction Patients is Feasible and Safe up to 5 Years of Follow-up

F. Rodrigo, Sander; van Ramshorst, Jan; E. Hoogslag, Georgette; Boden, Helèn; A. Velders, Matthijs; C. Cannegieter, Suzanne; Roelofs, Helene; Al Younis, Imad; Dibbets‐Schneider, Petra; E. Fibbe, Willem; Jan Zwaginga, Jaap; J. Bax, Jeroen; J. Schalij, Martin; L.M.A. Beeres, Saskia; E. Atsma, Douwe

doi:10.1007/s12265-013-9507-7

Public

Intramyocardial Injection of Autologous Bone Marrow-Derived Ex Vivo Expanded Mesenchymal Stem Cells in Acute Myocardial Infarction Patients is Feasible and Safe up to 5 Years of Follow-up

Published in Journal of Cardiovascular Translational Research • Aug 27, 2013

Authors:

Sander F. Rodrigo

Jan van Ramshorst

Georgette E. Hoogslag

Abstract

In experimental studies, mesenchymal stem cell (MSC) transplantation in acute myocardial infarction (AMI) models has been associated with enhanced neovascularization and myogenesis. Clinical data however, are scarce. Therefore, the present study evaluates the safety and feasibility of intramyocardia...

Subject

Medicine

Myocardial infarction

Mesenchymal stem cell

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