Fractionation of Aqueous Cigarette Tar Extracts: Fractions That Contain the Tar Radical Cause DNA Damage

Previously, we have shown that aqueous cigarette tar (ACT) extracts contain a long-lived tar radical that associates with DNA in isolated rat alveolar macrophages and causes DNA damage in isolated rat thymocytes. These ACT solutions reduce oxygen to produce superoxide and, ultimately, hydrogen perox... View More