Sedation Agents Differentially Modulate Cortical and Subcortical Blood Oxygenation: Evidence from Ultra-High Field MRI at 17.2 T

Uhrig, Lynn; Ciobanu, Luisa; Djemaï, Boucif; Le Bihan, Denis; Jarraya, Béchir

doi:10.1371/journal.pone.0100323

Public

Sedation Agents Differentially Modulate Cortical and Subcortical Blood Oxygenation: Evidence from Ultra-High Field MRI at 17.2 T

Published in PLoS ONE • Jul 22, 2014

Authors:

Lynn Uhrig

Luisa Ciobanu

Boucif Djemaï

Abstract

BACKGROUND: Sedation agents affect brain hemodynamic and metabolism leading to specific modifications of the cerebral blood oxygenation level. We previously demonstrated that ultra-high field (UHF) MRI detects changes in cortical blood oxygenation following the administration of sedation drugs commo...

Subject

Isoflurane

Anesthesia

Medicine

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