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Gender-specific increase of bone mass by CART peptide treatment is ovary-dependent.

Published in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research • Dec 1, 2011
Authors:
Han Gerrits
,
Nicole Ec Bakker
,
Cindy Jm van de Ven-de Laat

Abstract

Cocaine- and amphetamine-regulated transcript (CART) has emerged as a neurotransmitter and hormone that has been implicated in many processes including food intake, maintenance of body weight, and reward, but also in the regulation of bone mass. CART-deficient mice are characterized by an osteoporot...

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