Protein Kinase A-Mediated Synapsin I Phosphorylation Is a Central Modulator of Ca<sup>2+</sup>-Dependent Synaptic Activity

Menegon, Andrea; Bonanomi, Dario; Albertinazzi, Chiara; Lotti, Francesco; Ferrari, Giuliana; Kao, Hung‐Teh; Benfenati, Fabio; Baldelli, Pietro; Valtorta, Flavia

doi:10.1523/jneurosci.3321-06.2006

Public

Protein Kinase A-Mediated Synapsin I Phosphorylation Is a Central Modulator of Ca2+-Dependent Synaptic Activity

Published in Journal of Neuroscience • Nov 8, 2006

Authors:

Andrea Menegon

Dario Bonanomi

Chiara Albertinazzi

Abstract

Protein kinase A (PKA) modulates several steps of synaptic transmission. However, the identification of the mediators of these effects is as yet incomplete. Synapsins are synaptic vesicle (SV)-associated phosphoproteins that represent the major presynaptic targets of PKA. We show that, in hippocampa...

Subject

Synapsin

Synapsin I

Exocytosis

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