Is Non-Homologous End-Joining Really an Inherently Error-Prone Process?

DNA double-strand breaks (DSBs) are harmful lesions leading to genomic instability or diversity.Nonhomologous end-joining (NHEJ) is a prominent DSB repair pathway, which has long been considered to be errorprone.However, recent data have pointed to the intrinsic precision of NHEJ.Three reasons can a... View More