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Derivation of pluripotent stem cells from cultured human primordial germ cells.

Published in Proceedings of the National Academy of Sciences of the United States of America • Nov 10, 1998
Authors:
M J Shamblott
,
J Axelman
,
S Wang

Abstract

Human pluripotent stem cells would be invaluable for in vitro studies of aspects of human embryogenesis. With the goal of establishing pluripotent stem cell lines, gonadal ridges and mesenteries containing primordial germ cells (PGCs, 5-9 weeks postfertilization) were cultured on mouse STO fibroblas...

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