Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease.

Yañez, Rosa; Luisa Lamana, María; García-Castro, Javier; Colmenero, Isabel; Ramírez, Manuel; A Bueren, Juan

doi:10.1634/stemcells.2006-0228

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Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease.

Shared by NobleBlocks on Nov 1, 2006 • 12:00 AM UTC

Authors:

Rosa Yañez

María Luisa Lamana

Javier García-Castro

Abstract

Previous studies have shown the relevance of bone marrow-derived MSCs (BM-MSCs) in controlling graft-versus-host disease (GVHD) after allogeneic transplantation. Since adipose tissue-derived MSCs (Ad-MSCs) may constitute a good alternative to BM-MSCs, we have expanded MSCs derived from human adipose...

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