Benefit of phosphodiesterase 4 inhibitors as supplemental therapy after lung transplantation concerning their antiproliferative effects: an experimental study using a heterotopic rodent model

Schade, Ina; Roth-Eichhorn, Sylke; Kasper, Michael; Kuss, Hildegard; Pl tze, Katrin; H. W. Funk, Richard; Sch ler, Stephan

doi:10.1097/00007890-200208150-00007

Public

Benefit of phosphodiesterase 4 inhibitors as supplemental therapy after lung transplantation concerning their antiproliferative effects: an experimental study using a heterotopic rodent model

Published in Transplantation • Aug 1, 2002

Authors:

Ina Schade

Sylke Roth-Eichhorn

Michael Kasper

Abstract

BACKGROUND: Recent advances in the understanding of immunomodulatory properties of phosphodiesterase 4 (PDE4) inhibitors recommend these drugs for immunosuppressive therapy after lung transplantation. The potency of three PDE4 inhibitors was tested using an established model of heterotopic tracheal ...

Subject

Rolipram

Roflumilast

Transplantation

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