Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

Zhang, Jieyuan; Guan, Junjie; Niu, Xin; Hu, Guowen; Guo, Shang; Li, Qing; Xie, Zongping; Zhang, Changqing; Wang, Yang

doi:10.1186/s12967-015-0417-0

Public

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

Published in Journal of Translational Medicine • Jan 31, 2015

Authors:

Jieyuan Zhang

Junjie Guan

Xin Niu

Abstract

BACKGROUND: Human induced pluripotent stem cell-derived mesenchymal stem cells (hiPSC-MSCs) have emerged as a promising alternative for stem cell transplantation therapy. Exosomes derived from mesenchymal stem cells (MSC-Exos) can play important roles in repairing injured tissues. However, to date, ...

Subject

Mesenchymal stem cell

Wound healing

Fibroblast

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