MF59®-Adjuvanted H5N1 Vaccine Induces Immunologic Memory and Heterotypic Antibody Responses in Non-Elderly and Elderly Adults

Banzhoff, Angelika; Gasparini, Roberto; Laghi‐Pasini, Franco; Staniscia, Tommaso; Durando, Paolo; Montomoli, Emanuele; Capecchi, Pamela; Di Giovanni, Pamela; Sticchi, Laura; Gentile, Chiara; Hilbert, Anke; Brauer, Volker; Tilman, Sandrine; Podda, Audino

doi:10.1371/journal.pone.0004384

Public

MF59®-Adjuvanted H5N1 Vaccine Induces Immunologic Memory and Heterotypic Antibody Responses in Non-Elderly and Elderly Adults

Published in PLoS ONE • Feb 6, 2009

Authors:

Angelika Banzhoff

Roberto Gasparini

Franco Laghi‐Pasini

Abstract

BACKGROUND: Pathogenic avian influenza virus (H5N1) has the potential to cause a major global pandemic in humans. Safe and effective vaccines that induce immunologic memory and broad heterotypic response are needed. METHODS AND FINDINGS: Healthy adults aged 18-60 and > 60 years (n = 313 and n = 173,...

Subject

Vaccination

Medicine

Immunogenicity

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