MF59-adjuvanted H5N1 vaccine induces immunologic memory and heterotypic antibody responses in non-elderly and elderly adults.

A, Banzhoff; R, Gasparini; F, Laghi-Pasini; T, Staniscia; P, Durando; E, Montomoli; PL, Capecchi; Giovanni P, di; L, Sticchi; C, Gentile; A, Hilbert; V, Brauer; S, Tilman; A, Podda

doi:10.1371/journal.pone.0004384

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MF59-adjuvanted H5N1 vaccine induces immunologic memory and heterotypic antibody responses in non-elderly and elderly adults.

Shared by NobleBlocks on Feb 6, 2009 • 12:00 AM UTC

Authors:

Banzhoff A

Gasparini R

Laghi-Pasini F

Abstract

Background Pathogenic avian influenza virus (H5N1) has the potential to cause a major global pandemic in humans. Safe and effective vaccines that induce immunologic memory and broad heterotypic response are needed.Methods and findings Healthy adults aged 18-60 and > 60 years (n = 313 and n = 173, re...

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