Interleukin‐6 (IL‐6) functions as an in vitro autocrine growth factor in renal cell carcinomas

Miki, Shunji; Iwano, Masayuki; Miki, Yoshitsugu; Yamamoto, Masahiro; Tang, Bo; Yokokawa, Kiyoshi; Sonoda, Takao; Hirano, Toshio; Kishimoto, Tadamitsu

doi:10.1016/0014-5793(89)80805-1

Public

Interleukin‐6 (IL‐6) functions as an in vitro autocrine growth factor in renal cell carcinomas

Published in FEBS Letters • Jul 3, 1989

Authors:

Shunji Miki

Masayuki Iwano

Yoshitsugu Miki

Abstract

Interleukin-6 (IL-6) was found to be a growth factor of renal cell carcinomas Furthermore, renal cell carcinomas freshly isolated from the patients expressed mRNA of IL-6 and secreted biologically active IL-6 under the culture conditions where the tumor cells could grow, but they did not produce IL-...

Subject

Autocrine signalling

Cancer research

In vitro

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!