Neoadjuvant treatment for unresectable rectal cancer: an interim analysis of a multicentre randomized study.

K, Bujko; A, Nasierowska-Guttmejer; L, Wyrwicz; M, Malinowska; J, Krynski; E, Kosakowska; A, Rutkowski; L, Pietrzak; L, Kepka; J, Radziszewski; M, Olszyna-Serementa; M, Bujko; A, Danek; M, Kryj; J, Wydmanski; W, Zegarski; W, Markiewicz; T, Lesniak; I, Zygulski; D, Porzuczek-Zuziak; M, Bebenek; A, Maciejczyk; W, Polkowski; B, Czeremszynska; E, Cieslak-Zeranska; Z, Toczko; A, Radkowski; L, Kolodziejski; M, Szczepkowski; A, Majewski; M, Jankowski

doi:10.1016/j.radonc.2013.03.001

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Neoadjuvant treatment for unresectable rectal cancer: an interim analysis of a multicentre randomized study.

Shared by NobleBlocks on Apr 13, 2013 • 12:00 AM UTC

Authors:

Bujko K

Nasierowska-Guttmejer A

Wyrwicz L

Abstract

Purpose To present an interim analysis of the trial comparing two neoadjuvant therapies for unresectable rectal cancer.Methods Patients with fixed cT3 or cT4 or locally recurrent rectal cancer without distant metastases were randomized to either 5 × 5 Gy and 3 courses of FOLFOX4 (schedule I) or 50.4...

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