Epirubicin and Cyclophosphamide, Methotrexate, and Fluorouracil as Adjuvant Therapy for Early Breast Cancer

Poole, Christopher; Earl, Helena; Hiller, Louise; Dunn, Janet; Bathers, Sarah; Grieve, Robert; Spooner, D.; K. Agrawal, R.; Fernando, Indrajit; Murray Brunt, Adrian; O'Reilly, S.M.; M. Crawford, S.; Rea, Daniel; Simmonds, Peter; Mansi, Janine; Stanley, Andrew; Harvey, Peter; McAdam, Karen; Foster, Liz; Leonard, Robert; Twelves, Christopher

doi:10.1056/nejmoa052084

Public

Epirubicin and Cyclophosphamide, Methotrexate, and Fluorouracil as Adjuvant Therapy for Early Breast Cancer

Published in New England Journal of Medicine • Nov 2, 2006

Authors:

Christopher Poole

Helena Earl

Louise Hiller

Abstract

BACKGROUND: The National Epirubicin Adjuvant Trial (NEAT) and the BR9601 trial examined the efficacy of anthracyclines in the adjuvant treatment of early breast cancer. METHODS: In NEAT, we compared four cycles of epirubicin followed by four cycles of cyclophosphamide, methotrexate, and fluorouracil...

Subject

Epirubicin

Medicine

Internal medicine

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